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Liver Function Test - Rs.450 Only

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Liver Function Tests measure various chemicals in the blood made by the liver. An abnormal result may indicate a problem with your liver and may help to identify the cause.

Commonly used tests to check liver fuction are the alanine transaminase(ALT), Aspartate aminotransferase(AST), albumin and bilirubin tests. The ALT and AST tests measure enzymes that your liver releases in response to damage or disease. Measure the severity of a disease, particularly scarring of the liver(cirrhosis).

The liver has many functions that are vital to life. Briefly , some of the important function of the human liver are :

Detoxification of blood

  • Production of important clotting factors, albumin, and many other important protiens.
  • Metabolizing medications and nutrients.
  • Processing of waste products of hemoglobin and other cells.
  • Storing of vitamins, fats, cholesterol and bile.
  • Production of glucose.

Symptoms of liver disease:-

  • Jaundice(a yellow discoloration of the skin due to elevated bilirubin concentrations in the blood stream)
  • Abdominal pain & swelling
  • Confusion
  • Bleeding
  • Fatigue and weight loss
  • Alcohol can be toxic to the liver(hepatotoxic), especially in high doses and long term alcohol abuse is a common
  • Loss of appetite
  • Nausea , vomitting
  • Dark urine, light coloured stool
  • Itching
  • Diarrhea

Cost of liver function tests - Rs.450/- Through pathlab 360 you get 50% discount.

The tests included in the profile are as follows:

  • ALT
  • AST
  • Bilirubin(total,direct,indirect)
  • GGT
  • LDH
  • Protien (total, albumin, globullin, AG ratio)
  • Alkaline phosphatose

Liver tests may be done together in a panel or tested separately-some common liver function tests include.

When liver cells are damaged or destroyed, the enzymes in the cells leak out into the blood, where the can be measured by blood tests, Liver tests check the blood for two main liver enzymes.

Aspartate aminotransferease (AST), formerly called SGOT. The AST enzyme is also found in muscles and many other tissues beside the liver.

Alkanine aminotransferase (ALT), formerly called SGPT. ALT is almost exclusively found in the liver. If ALT & AST are found together in elevated amounts in the blood, liver damage is most likely present.

Alkaline phosphate (ALP) is an enzyme in the liver,bile ducts and bone. Higher than normal levels of ALP may indicate liver damage or disease , such as blocked bile duct, or certain bone diseases.

Albumin and total protein albumin is one of several proteins made in the liver and your body needs these proteins to fight infections and to perform other functions. Lower than normal levels of albumin and total protein may indicate liver damage or diseases.

Bilirubin – It is a substance produced during the normal breakdown of red blood cells. Bilirubin passes through the liver and is excreted in stool. Elevated levels of bilirubin(Jaundice) may indicate liver damage or disease.

Gamma –glutamyltransferase (GGT). GGT is an enzyme in the blood. Higher than normal levels may indicate liver or bile duct damage.

L –lactate dehydrogenase (LDH)- It is an enzyme found in the liver. Elevated levels may indicate liver damage.

Prothrombin time(PT)- PT is the time it takes your blood to clot. Increased may indicate liver damage.

International normalized ratio (INR) – Not really a test, but a standarized way for all lab to report PT, so their results can be compared accurately with each other.

OPT and INR rise in people with severe liver disease because the liver fails to make normal amounts of certain clotting factors. As elevated PT can have many other causes besides liver disease.

Normal blood tests results for typical liver function tests include:

  • ALT 7 to 55 units per liter (U/L)
  • AST 8 to 48 U/L
  • ALP 45 to 115 U/L
  • Albumin 3.5 to 5.0 grams per deciliter(g/dl)
  • Total protien-6.3 to 7.9 g/dl
  • Bilirubin 0.1 to 1.0 mg/dl
  • GGT 9 to 48 U/L
  • LDH-122 to 222 U/L
  • PT-9.5 to 13.8 seconds

These results are typical for adult men. Normal results may vary slightly from laboratory to laboratory to laboratory and be slightly different for women and children. Result may also be affected by certain foods or medications you’ve eaten of taken so that your doctor can correctly interpret your results.

Preparation:

Patient should not take anything before the testing. He/she can only take water. There is typical fasting for 8-12 hours before the testing.

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